Peptides for Weight Loss: Here is What You Need to Know

Have you ever heard about the peptides for weight loss, which are short strings of amino acids, that help lose weight? If not, then this article has a complete guide for you if you are worried about your high weight.

Peptides are involved in stimulating the release of GLP-1 and Human growth hormones involved in optimizing body metabolism, decreasing weight, maintaining lean mass, and increasing collagen production.

Peptides are available in capsule, injectables, and powder form to increase the hormone release. Moreover, peptides are more easily absorbed and utilized by the body and are potentially effective.

Can peptide therapy be used in reducing weight loss?

Yes! peptides are effective in losing weight but not all peptides are effective in reducing weight. These weight-losing peptides act on GLP receptors. Insulin is released by these peptides by which blood glucose level is controlled.

They also slow down bowel movements due to which the digestion of food slows down and food remains inside the body for a longer period, reducing the appetite and people do not have cravings for anything else.

Peptides always do not help in reducing weight, instead, several other factors are also involved, which include diet, exercise, a person’s medical history, genetics, person’s habits, and a person’s reaction to drugs.

How can peptide therapy be used to decrease weight?

Peptide therapy can help decrease weight in a variety of ways, including;

1. By Increasing the production of HGH

By the increase of HGH hormones, the body gains strength and energy which improves the body’s activity and helps in working out and decreasing calories.

2. By decreasing body fat and maintaining lean mass

Peptides will help break fats which would lead to a decrease the body weight.

3. By targeting specific receptors

Peptides will target specific receptors like GLP-1 which would lead to a decrease the appetite and increase the metabolism of carbohydrates and fats.

The Common Types of peptides for weight loss?

Some of the peptides that are most effective in reducing weight are discussed here:

1. Semaglutide

A GLP-1 receptor agonist, which comes under the brand name of Ozempic or Wegovy.

Ozempic is used to treat Type 2 diabetes. According to the Ozempic website, a person can reduce 14 pounds by using it.

Wegovy is useful in treating obesity. A and according to the Wegovy website, a person can reduce 15% of body weight on medication.

Both drugs are approved by the Food and Drug Administration. GLP-1 is a naturally occurring hormone and semaglutide helps in regulating appetite by mimicking the effects of GLP-1.

2. Liraglutide

Another GLP-1 receptor agonist, which is given in injection form once daily, is effective in weight loss because it decreases appetite. Both semaglutide and liraglutide are given for weight loss but semaglutide is more value for money. Liraglutide comes under the brand name Saxenda.

3. Tirzepatide

Just like semaglutide and liraglutide, tripeptide also acts on GLP-1 receptors, but it also acts on an additional receptor called GIP. It comes under the brand names of Mounjaro and Zepbound.

Mounjaro is FDA-approved and is useful in the treatment of type 2 diabetes whereas Zepbound is used in reducing weight. According to the Zepbound website, people can reduce 45 pounds of weight during 17 months of clinical trials by using it.

4. CJC1295 Ipamorline

The production of growth hormone and IGP-1 is stimulated by these two chained peptides which decrease the body fats, increase the lean mass, and improve sleep quality and cognition.

5. AOD 9604

These are called anti-obesity drugs and are used in decreasing fat mass. They don’t increase the secretion of growth and control the way the natural growth hormone regulates fat metabolism. It is used in injection form and does not increase hunger and cortisol levels.

6. MOTS-C

Derived from mitochondria and as a mitochondrial-deprived peptide, it optimizes glucose metabolism and is beneficial for diabetes, obesity, and aging. Having a big effect on cellular and systemic levels, it acts as an exercise mimetic and increases the effects of exercises.

It reduces the risk of inflammation, cardiovascular disease, diabetes, and insulin resistance and increases energy production along with promoting neuroprotection.

7. Tesamorelin

It boosts metabolism and muscle growth which would help in decreasing belly fat and weight circumference. It also increases the pituitary release of growth hormones, which would burn calories. It also increases the IGP-1 which reduces blood sugar levels and enhances weight loss.

Benefits of peptides for weight loss

Peptides have several benefits in losing body weight, some of which are discussed:

1. Boost energy

By the process of fat oxidation, peptides break down the stored fats into fatty acids and also Improve the uptake of glucose to produce energy. These processes would lower the risk of obesity and energize the body

2. Improve youthful skin

Peptides improve the formation of collagen in the skin, which is 3 chained polypeptides. As a person ages, collagen production decreases leading to the formation of wrinkles and dullness. Peptides support collagen formation and provide glow to the skin.

3. Improve muscles and Joint pain

The peptides can increase the recovery of tissue through growth hormones. It would help in increasing the muscle cells, rejuvenating the joints, and strengthening the muscles. MGF, thymosin beta 4, IGF-1, and ipamorelin are best for muscle regeneration.

4. Hormones balancing

Peptides are involved in hormonal balance inside the body and are essential for their formation. Hormones that are required in our body, form more at younger ages but as our age advances, the level of hormone formation becomes less.

Just take the example of growth hormone, which is produced in large amounts at a young age when it is not required that much whereas in older age, lack of this hormone will lead to a drastic impact on the body. With the help of peptides, these hormones can meet the needs of our bodies.

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5. Enhance memory and brain function

Peptides help promote brain health and improve cognition, brain function, and memory. Peptides like NAP are involved in decreasing the risk of neurodegenerative diseases like dementia and Parkinson’s disease. Physical activity of the brain can be improved by IGF-1. High IGF-1 improves the cognition activity. Neuropeptides like galanin and ghrelin help increase cognitive activity.

6. Improve sleep quality

Sleep-related hormones are involved in improving the quality of sleep. The GHRH (growth hormone releasing hormone) increases the secretion of growth hormones while the CRH (corticotropin-releasing hormone) improves the rapid eye movement sleep. When there is an imbalance between these hormones, sleep will get disturbed. Consequently, we experience impaired sleep, cortisol, depression, and aging.

7. Promote healthy libido

The peptides are helpful for healthy libido and sexual arousal. the libido decreases as the advances and several problems like erectile dysfunctions and hormonal imbalance occur.

Peptides like kisspeptin are helpful to increase libido in women. PT-141 increases sexual energy even with the advancing age. PT-141 regulates the formation of nitric oxide inside the body which expands the blood vessels and allows the blood to circulate.

8. Raises mitochondrial count

With the neuropeptides, the mitochondrial count is increased. Mitochondria are the powerhouse of the cells and our cells age, deteriorate, and die. Therefore, peptides prevent these degenerative effects by increasing the mitochondrial count and protecting the chronic disease and fatigue.

9. Fat burning

The target of peptides is fat cells and these promote the breakdown of stored fats which results in weight loss.

10. Appetite suppression

Peptides can decrease appetite by controlling hunger hormones.

11. Increases metabolism

Certain peptides lead to enhanced metabolism in rest, which is essential for reducing weight.

Potential side effects of peptides for weight loss

Side effects of peptides may include the following;

1. Nausea and gastrointestinal problems

Peptides, that act on GLP-1 receptors can cause nausea, vomiting, and gastrointestinal problems like gastroparesis, and pancreatitis.

2. Hypoglycemia

Peptides that lower the blood glucose level can cause hypoglycemia, fatigue, and dizziness.

3. Insulin resistance

As insulin is involved in storing blood glucose into glycogen, certain peptides are used for insulin resistance and insulin sensitivity, which after stopping the weight loss, are used to increase the weight.

4. Allergic reactions

Some peptides may also cause allergic reactions.

What factors are required for choosing peptides for weight loss?

Several factors are seen before starting the peptide treatment. These factors include your goal of decreasing weight, your health & fitness level or profile, and your medical history. Except for all these factors, the peptides can be chosen in a way that either you prefer taking them orally or in the form of injectables.

Do we need a prescription to get peptides for weight loss?

Yes! To start peptide therapy, one can get a prescription from his health care provider or doctor. The peptide therapy can be prescribed based on patient requirements.

For example, Zepbound is a weight-reducing peptide, that is given in the case of obesity (with a BMI more than 30) or in the case of overweight (with a BMI of more than 27) with weight-related problems like type 2 diabetes, high blood pressure, and cholesterol.

For any information, you can call your health care provider, who can use integrative as well as holistic approaches and can choose the right sort of peptide for you to lose weight.

Conclusion

Peptides are useful in reducing weight. Peptides perform their functions by reducing gut movement and by targeting GLP-1 receptors. Peptides also stimulate the release of human growth hormones and are involved in boosting immunity, preserving lean mass, decreasing fats, and improving libido.

They also decrease the risk of diabetes by regulating blood sugar levels. Moreover, the use of peptides involves several factors which include age, health profile, and medical history. Peptides are not always safe to use but they have many side effects and should not be used without a physician’s prescription.